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MONONINE NOVOSEVEN SOLR PROPLEX -T RECOMBINATE SOLR REFACTO PLATELET AGGREGATION INHIBITORS DIPYRIDAMOLE TABS PLAVIX TABS TICLOPIDINE HCL TABS PLATELET AGGR. INHIBITORS COMBO'S - MISC. AGGRENOX CP12 PENTOXIFYLLINE ER TBCR PLETAL TABS HEMOSTATIC HEMOSTATIC AMICAR AMINOCAPROIC ACID OPHTHALMICS OP. - ANTIBIOTICS AK-SPORE OINT BACITRACIN OINT BACITRACIN NEOMYCIN POLYM BACITRACIN POLYMYXIN B OINT CHLOROPTIC SOLN ERYTHROMYCIN OINT GENTAMICIN SULFATE NEOMYCIN POLYMYXIN GRAMIC NEOSPORIN SOLN POLYSPORIN SODIUM SULFACETAMIDE SOLN SULFACETAMIDE SODIUM TERRAMYCIN OINT TOBRAMYCIN SULFATE SOLN TRIMETHOPRIM SULFATE POLY VIROPTIC SOLN OP. - QUINOLONES 1 CILOXAN OINT CILOXAN SOLN OCUFLOX SOLN VIGAMOX QUIXIN SOLN ZYMAR Step order must be followed to Preferred drugs must be tried in step-order and failed due to lack of efficacy or intolerable side effects before non-preferred drugs will be approved, unless an avoid PA. Must fail Ocuflox, acceptable clinical exception is offered on the Prior Authorization form, such as the presence of a condition that prevents usage of the preferred drug or a Vigamox, and a Ciloxan significant potential drug interaction between another drug and the preferred drug s ; exists. product before moving to next step product without PA. Use PA Form # 20420 AK-POLY-BAC OINT AK-SULF OINT AK-TOB SOLN BLEPH-10 SOLN GENTAK ILOTYCIN OINT NEOMYCIN BACI POLYM OINT NEOSPORIN OINT OCUSULF-10 SOLN OCUTRICIN SOLN TERAK OINT TOBREX OINT TRIFLURIDINE SOLN Use PA Form # 20420 or 10220 Preferred drugs must be tried and failed due to lack of efficacy or intolerable side effects before non-preferred drugs will be approved, unless an acceptable clinical exception is offered on the Prior Authorization form, such as the presence of a condition that prevents usage of the preferred drug or a significant potential drug interaction between another drug and the preferred drug s ; exists. AGRYLIN CAPS TRENTAL TBCR Use PA Form # 20420 or 10220 PERSANTINE TABS TICLID TABS Use PA Form # 20420 or 10220 Preferred drugs must be tried and failed due to lack of efficacy or intolerable side effects before non-preferred drugs will be approved, unless an acceptable clinical exception is offered on the Prior Authorization form, such as the presence of a condition that prevents usage of the preferred drug or a significant potential drug interaction between another drug and the preferred drug s ; exists. Jami rubin morgan stanley can you hear me. Brain edema and perivascular lymphocytosis: other than occasional anecdotal reports, there is little to be found in the medical literature implicating vaccines in causing brain edema and perivascular meningeal lymphocytic infiltrations in humans, probably because the phenomenon has never been systematically studied.
Special offer: $ 01 per pill pletal pletal cilostazol ; reduces attacks of intermittent claudication that may occur after walking.

Dosages may vary for elderly patients or for those with hepatic or renal insufficiency. The date that the drug was first approved by the FDA for any indication. Accelerated infusion: for patients 67 kg, 100 mg as a 15-mg IV bolus, then 50 mg over 30 min, then 35 mg over 60 min; for patients 67 kg, 15-mg IV bolus, then 0.75 mg kg over 30 min not to exceed 50 mg, then 0.50 mg kg over 60 min not to exceed 35 mg. 3-h infusion: 100 mg administered as 60 mg in the first hour, 20 mg over the second hour, and 20 mg over the third hour. DVT, deep vein thrombosis; HIT, heparin-induced thrombocytopenia; IU, international units; PAD, peripheral arterial disease; PCI, percutaneous coronary intervention; PE, pulmonary embolism; po, by mouth; PTCA, percutaneous transluminal coronary angioplasty; qd, daily; SC, subcutaneous. Drug manufacturers: Plavix Sanofi Pharmaceuticals Inc., New York, NY ; , Reopro Centocor B.V., Leiden, The Netherlands ; , Aggrastat Merck & Co., Inc., West Point, PA ; , Integrilin COR Therapeutics Inc, South San Francisco, CA and Key Pharmaceuticals Inc., Kenilworth, NJ ; , Lovenox Rhone-Poulenc Rorer Pharmaceuticals Inc., Collegeville, PA ; , Fragmin Pharmacia and Upjohn, Kalamazoo, MI ; , Normiflo Wyeth-Ayerst, Philadelphia, PA ; , Refludan Hoechst Marion Roussel Inc., Kansas City, MO ; , Orgaran Organon Inc., Leiden, The Netherlands ; , Activase Genentech Inc., South San Francisco, CA ; , Eminase Wulfing Pharmaceuticals GmbH, Groneo, Germany ; , Pletao Otsuka Pharmaceuticals Co., Ltd., Tokoshima, Japan ; , Trental Hoechst Marion Roussel Inc., Kansas City, MO ; , Abbokinase Abbott Laboratories North Chicago, IL. During the 2007-08 year, the anderson school will be celebrating its vicennial and cyklokapron.

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With Gates Foundation funding to the Liverpool node we have engaged 12 students linked to country programmes ensuring criteria of involvement are directly applicable to implementation ; developed distance learning materials with WHO and the Wellcome Trust, and are pioneering web-based information on communicable diseases filariasis continue to work on LF prevalence data to determine if the distribution could be attributed to environmental or entomological characters. The current distribution of filariasis and malaria in West Africa suggests that prevalence could be correlated with An. gambiae cytoform distribution as opposed to environmental factors such as vegetation and copegus.
The information in this section is subject to consultation prior to definitive publication. Comments, which are invited at this stage, should be referred to: Division of Drug Management & Policies World Health Organization 1211 Geneva 27, Switzerland. Plaintiff and the Class are obligated to reimburse their plan members for Nexium, when an equivalent over the counter version of the h-ug is available at no cost to Plaintiff and members of the Class, and a generic version is available at a substantial savings. 142. But for the success of AstraZeneca's tortious interference, Plaintiff and members and epivir-hbv.

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Articles to help you and your family gain the knowledge necessary, in order to take positive steps towards maximum health and longevity. "The Natural Health Hour" can be heard every Saturday from 8am to 9am EST on WBZT 1230AM ; southeast Florida, WVNJ 1160AM ; in New Jersey, New York and Connecticut and listeners in the Boulder and Denver area can catch the show on KRKS 94.7FM ; or KNUS 710AM ; . If you are outside of these listening areas or if you would like friends or relatives to listen to the.

Healthcare providers stated that they trust the government and its role in managing Armenia's healthcare services and in developing rules for drug donations. Healthcare managers stated that MOH regulations which include the WHO Guidelines ; , which could reduce the level of donations, have not done so since HAO has implemented them selectively and flexibly. The director of the Office of Humanitarian Assistance has used the exceptions in the regulations including, for example, authorizing the donation of drugs with less than 12 months dating and drugs that are not listed on the EDL. Administrators and pharmacists stated that they share and barter ; among facilities donated drugs that do not meet the needs of a facility to which they were allocated and exelon.

ADP stands for Adenosine Diphosphate. See Training Manual for additional information on ADP Inhibitors. The following drugs should be captured as ADP Inhibitors: Plavix or Clorpidogrel Ticlid or Ticlodipine Pl4tal or Cilostazol The following drugs should not be captured as ADP Inhibitors: Persantine or Dipyridimole Aggrenox aspirin + extended release Dipyridimole ; Can you explain why Plavix is only coded as At the time Plavix was added to the data set as yes if it is within 24 hours? Plavix's half life is a preoperative medication, the 24 hour window much longer and has significant effect on was applicable with the dosing and perioperative bleeding and blood utilization? administration at that time. Because of the Even STS recommendations are to stop 5 evolution in usage of Plavix, the 24 hour days preop. ASA is coded yes for a 5 day time window does not make sense. Will change for frame and is not nearly as disruptive to periop the next spec upgrade. coagulation. Should Aggrenox be coded as ASA? Combo drugs are not listed in that section!


References Facts and Comparisons. 4.0.; Wolters Kluwer Health, Inc; 2006. : online.factsandcomparisons . Accessed December 2006 Thompson MICROMEDEX on-line 1974-2006. Accessed December 2006. Money SR et al. Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease. J Vasc Surg. 1998; 27: 267-275. Claugett GP et al, Antithrombotic Therapy in Peripheral Arterial Occlusive Disease: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004; 126 3 Suppl ; : 609S-26S. Thompson PD et al. Meta-analysis of results from eight randomized, placebo-controlled trials on the effect of cilostazol on patients with intermittent claudicaation. J Cardiol. 2002; 90 12 ; : 1314-9. Hirsch AT et al, ACC AHA 2005 practice guidelines for the management of patient with peripheral arterial disease lower extremity, renal, mesenteric, and abdominal aortic ; : a collaborative report from the American Association for Vascular Surgery Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC AHA Task Force on Practice Guidelines Writing Committee to Develop Guidelines for the Management of Patients with Peripheral Arterial Disease ; . Circulation. 2006; 113: e463-e654. Poetal Package Insert ; . Rockville, MD; Otsuka America Pharmaceutical, 2005. Trental Packege Insert ; . Bridgewater, NJ; Aventis Pharmaceuticals, April 2004 and kytril.

34. Stevens, D.A., and B. H. Aristizabal. 1997. In vitro antifungal activity of novel azole derivatives with a morpholine ring, UR-9746 and UR-9751, and comparison with fluconazole. Diagn. Microbiol. Infect. Dis. 29: 103-106. Cilostazol is contraindicated in patients with congestive heart failure CHF ; of any severity. Cilostazol and several of its metabolites are inhibitors of phosphodiesterase III. Several drugs with this pharmacological effect have caused decreased survival compared with placebo in patients with class IIIIV CHF. In patients without CHF, the long-term effects of PDE III inhibitors including PLETAL ; on survival are unknown. Drug Interactions39-44 and leukeran. 1. Is the patient being treated concomitantly with oral corticosteroids, anticoagulants warfarin or heparin ; , or antiplatelets Ticlid, Plavix, or Pletla ; ? 2. Has the patient tried and failed therapy with two prescription strength nonsteroidal anti-inflammatory drug NSAID ; within the past six months for this condition? If yes, please provide the names of the drugs, including strength and dosage 3. Is the patient currently receiving a GI protective agent? 4. Is the patient on concomitantly aspirin therapy?.
Vicky gave the group details of new projects which she will be offering to practices. Audit of Once Weekly Medicines Vicky can help practices to identify patients taking drugs which are only intended for once weekly administration, and check for appropriate directions and quantities. Blood Glucose Monitoring Strips Audit Vicky can identify patients currently testing their blood glucose and issue guidance on appropriate frequency for monitoring and the correct technique for finger-pricking. Review of Treatment Room Dressings Available January 2006 ; . NHSSB launched the Wound Care Formulary in 2004, and to assist with the implementation Vicky will check dressings stocked in the practice and make recommendations for improving compliance with the evidence-based choices. 5. Recent SMC recommendations SMC have recently made recommendations on several drugs. Although their guidance is aimed at the NHS in Scotland it can be a useful guide to good practice for prescribers here: a ; Diclofenac Voltarol Gel Patch ; SMC recommend that they should not be prescribed as they have no benefits over diclofenac gel and are 40% more expensive. b ; Pregabalin Lyrica ; Not recommended for pain caused by damage to peripheral nerves. SMC did not consider that clinical or cost-effectiveness had been shown. c ; Cilostazol Pleral ; Not recommended for use to improve maximal and pain-free walking distances in patients with intermittent claudication, who do not have rest pain and who do not have evidence of peripheral tissue necrosis and viramune. Closure to my leg pain and varicose veins.

Pletal intermittent claudication

DOSAGE AND ADMINISTRATION The recommended dosage of PLETAL is 100 mg b.i.d. taken at least half an hour before or two hours after breakfast and dinner. A dose of 50 mg b.i.d. should be considered during coadministration of such inhibitors of CYP3A4 as ketoconazole, itraconazole, erythromycin and diltiazem, and during coadministration of such inhibitors of CYP2C19 as omeprazole. Patients may respond as early as 2 to weeks after the initiation of therapy, but treatment for up to 12 weeks may be needed before a beneficial effect is experienced. -8 and mysoline and Order pletal online.

Preoperative Evaluation Make an appointment with your primary care physician for a preoperative evaluation within 30 days of surgery. The evaluation will include the following: - A physical examination - A health history - EKG if over 40 years of age or with history of heart disease ; - Chest X-ray with history of lung disease ; - Review of current medications - Bloodwork including type and crossmatch Medications to Avoid Before Surgery: Medications to discontinue or continue will be discussed with your primary care physician. Ten to 14 days before surgery, all medications that may cause "thinning" of the blood should be stopped. This includes prescription and non-prescription drugs such as: Coumadin Warfarin ; Plavix Persantine Lovenox Fragmin Pletal Gingko Biloba Vitamin E tocopherol ; All drugs containing aspirin All non-steroidal anti-inflammatory drugs NSAID's ; Herbal stimulants Trental. 1% crm; 2.5% 1% crm, lot 1% 10% crm 0.5%, 1%, 2.5% OTC products are NOT covered. crm, lot, oint 1, 2.5% crm Consider generic equivalent. 0.5% 3% crm, lot Consider generic equivalent. 1% 2.5% crm, lot, oint 1% oint 0.05% 1% crm, lot C oint 0.05% 1% crm, Consider generic equivalent, other generics, or other lot brand products in this class. 100, 000 units 1 mg cream, ointment 0.25%, 0.5%, 0.7 INJ 1%, 1.5%, 2%, % INJ Consider generic alternatives and oxytrol.

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The painful symptoms that you are having may be a neuropathy that occurs in a minority of rls sufferers. With healthy eating, good lifestyle habits and well-controlled blood glucose, you'll be as healthy as you can be.

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Targeted tuberculin testing for LTBI is a strategic component of tuberculosis TB ; control that identifies persons at high risk for developing TB who would benefit by treatment of LTBI, if detected. Persons with increased risk for developing TB inThis Statement is one of four Statements on the diagnosis, treatment, prevention, and control of tuberculosis. The Statement updates and revises information on the treatment of latent tuberculosis infection in 1 ; Treatment of tuberculosis and tuberculosis infection in adults and children. Am.1. Respir. Crit. Care Med. 1994; 149: 1359-1374, and information on screening for tuberculosis in 2 ; Control of tuberculosis. Am. Rev. Respir. Dis. 1992; 146: 1623-1633. For information on the treatment of tuberculosis, refer to 1 ; . For information on management of contacts and organization of control programs, refer to 2 ; . For information on diagnostic methods, refer to 3 ; Diagnostic standards and classification of tuberculosis in adults and children. Am Respir. Crit. Core Med. 2000; 161 : 1376-l 395. J Respir Crit Care Med Vol 161. pp S221-5247, 200O Internet address: atsjournals. Glenn Reicin STEP Commentary: Changes to Growth STEP Glenn Reicin STEP Commentary: Changes to Growth STEP Glenn Reicin Hosp. Supplies & Medical Technology: 2005 DRG Reimbursement Rates: Few Surprises Glenn Reicin Biomet: F1Q05 - Our Initial Take on the Quarter Glenn Reicin Biomet: F1Q05: Gaining Some Traction Glenn Reicin Biomet: F1Q05: Gaining Some Traction Marc Biovail: Low Quality 2Q04 Goodman Earnings Marc Biovail: 2Q04 Earnings In-Line Goodman as Transition Continues Marc Goodman Marc Goodman Marc Goodman Ole Slorer Biovail: Tiazac XC Approved in Canada EPS Revisions from ModelWare Rollout Biovail: Management Confirms EPS, but Components Change Strategy: Weekly Technical Perspecives A Question of Commitment Oil Services Equipment: Equipment, Jackup Rates, and US Oil Inventory Revisions Oil Services Equipment: US Land Rig Count Expected to Far Exceed Recent 2001 High Oil Services Equipment: Accelerating Drilling Points to Solid 2Q Earnings Season. Women still tend to marry men older than themselves; however, the gap between their median ages at first marriage has narrowed, from 7 years in the mid-1960s to 8 years in 200 world business competitiveness: how nz rates nz now ranks18th on the just-released world competitiveness scoreboard we've dropped two places. Herzog CA, Ma JZ & Collins AJ 2002 ; Comparative survival of dialysis patients in the United States after coronary angioplasty, coronary artery stenting, and coronary artery bypass surgery and impact of diabetes. Circulation 106: 220711. Higgins TL 2001 ; Daily versus admission mortality estimates: is admission severity yesterday's news? Crit Care Med 29: 20810. Higgins TL 1998 ; Quantifying risk and assessing outcome in cardiac surgery. J Cardiothorac Vasc Anesth 12: 33040. Higgins TL, Estafanous FG, Loop FD, Beck GJ, Blum JM & Paranandi L 1992 ; Stratification of morbidity and mortality outcome by preoperative risk factors in coronary artery bypass patients. A clinical severity score. JAMA 267: 23448. Higgins TL, Estafanous FG, Loop FD, Beck GJ, Lee JC, Starr NJ, Knaus WA & Cosgrove DM III 1997 ; ICU admission score for predicting morbidity and mortality risk after coronary artery bypass grafting. Ann Thorac Surg 64: 10508. Higgins TL & Starr NJ 1991 ; Risk stratification and outcome assessment of the adult cardiac surgical patient. Semin Thorac Cardiovasc Surg 3: 8894. Hill AB, Obrand D, O'Rourke K, Steinmetz OK & Miller N 2000 ; Hemispheric stroke following cardiac surgery: a case-control estimate of the risk resulting from ipsilateral asymptomatic carotid artery stenosis. Ann Vasc Surg 14: 2009. Hill AB, Obrand D & Steinmetz OK 1999 ; The utility of selective screening for carotid stenosis in cardiac surgery patients. J Cardiovasc Surg Torino ; 40: 82936. Hill SE, van Wermeskerken GK, Lardenoye JW, Phillips-Bute B, Smith PK, Reves JG & Newman MF 2000 ; Intraoperative physiologic variables and outcome in cardiac surgery: Part I. In-hospital mortality. Ann Thorac Surg 69: 10706. Hirose H, Amano A, Yoshida S, Takahashi A, Nagano N & Kohmoto T 2000 ; Coronary artery bypass grafting in the elderly. Chest 117: 126270. Hogue CW Jr, De Wet CJ, Schechtman KB & Davila-Roman VG 2003 ; The importance of prior stroke for the adjusted risk of neurologic injury after cardiac surgery for women and men. Anesthesiology 98: 8239. Hogue CW Jr & Hyder ml 2000 ; Atrial fibrillation after cardiac operation: risks, mechanisms, and treatment. Ann Thorac Surg 69: 3006. Hogue CW Jr, Murphy SF, Schechtman KB & Davila-Roman VG 1999 ; Risk factors for early or delayed stroke after cardiac surgery. Circulation 100: 6427. Hogue CW Jr, Sundt T 3rd, Barzilai B, Schecthman KB & Davila-Roman VG 2001 ; Cardiac and neurologic complications identify risks for mortality for both men and women undergoing coronary artery bypass graft surgery. Anesthesiology 95: 10748. Holzmann MJ, Ahnve S, Hammar N, Jorgensen L, Klerdal K, Pehrsson K & Ivert T 2005 ; Creatinine clearance and risk of early mortality in patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 130: 74652.

As displayed in the above table, these two trials had many differences. The patients in both groups were not exact. Patients may be enrolled in the CAPRIE trial up to 6 months after onset of stroke symptoms while only 3 months for the ESPS-2 study. Thus more stable patients may have been treated with clopidogrel. Also patients with TIA could be entered in the ESPS-2 trial but were not in the CAPRIE. In addition, various baseline patient demographics differed between the two groups. For instance, a higher portion of patients in the stroke subgroup of CAPRIE compared ESPS-2 were diabetic ~25% vs. 15.3%, respectively ; , had hypertension 65% vs. 61% ; or hypercholesterolemia 37.5% vs. 22.9% ; . Furthermore, the CAPRIE study was not powered to detect differences in the subgroups. Another difference was the overall dropout rates and those due to adverse effects between the two studies. These factors are important to consider in evaluating clopidogrel to DP-ASA. Until studies are conducted that directly compare these two agents, the specific differences in reducing the adverse events can only be speculated. O. Other Antiplatelet Agents: Pentoxifylline Trental ; and Cilostazol Pletal ; 1. Pentoxifylline Trental ; Pharmacology: Classified as a methylxanthine derivative. The exact mechanism has not been determined, but appears to stimulate prostacyclin release from vascular tissue. This agent also has several effects on erythrocytes increases flexibility and reduces whole blood viscosity ; and decreases plasma hypercoagulability.108, 109 Indication: Treat intermittent claudication associated with peripheral vascular disease.108 Efficacy: Pentoxifylline appears to increase initial and intolerable claudication distances, plus reduce the severity and occurrence of paresthesia. Although, pentoxifylline does not appear more effective than placebo in relieving other symptoms that include cramping, pain during exercise, and tiredness.25, 109 According to the ACCP guidelines for chronic extremity arterial insufficiency, results of studies do not consistently document a benefit with pentoxifylline. Although some patients who are unable to partake in exercise therapy may see an improvement in walking distances. Otherwise, "pentoxifylline should not be routinely used in patients with intermittent claudication grade 1B ; ."25 2. Cilostazol Pletal ; Pharmacology: Classified as a quinolinone-derivative selective phosphodiesterase inhibitor; this agent inhibits platelet aggregation and vasodilates arteries.110, 111 Indication Contraindication: Treat intermittent claudication; this agent is contraindicated in patients with congestive heart failure.110. NDA 20-863 S-011 Page 5 2. Diltiazem: Diltiazem 180 mg decreased the clearance of cilostazol by ~30%. Cilostazol Cmax increased ~30% and AUC increased ~40% see DOSAGE AND ADMINISTRATION ; . 3. Grapefruit Juice: Grapefruit juice increased the Cmax of cilostazol by ~50%, but had no effect on AUC. Inhibitors of CYP2C19: Omeprazole: Coadministration of omeprazole did not significantly affect the metabolism of cilostazol, but the systemic exposure to 3, 4-dehydro-cilostazol was increased by 69%, probably the result of omeprazole's potent inhibition of CYP2C19 see DOSAGE AND ADMINISTRATION ; . Quinidine: Concomitant administration of quinidine with a single dose of cilostazol 100 mg did not alter cilostazol pharmacokinetics. Lovastatin: The concomitant administration of lovastatin with cilostazol decreases cilostazol Css, max and AUC by 15%. There is also a decrease, although nonsignificant, in cilostazol metabolite concentrations. Coadministration of cilostazol with lovastatin increases lovastatin and -hydroxi lovastatin AUC approximately 70%. This is most likely clinically insignificant. CLINICAL EFFICACY The ability of Pletal to improve walking distance in patients with stable intermittent claudication was studied in eight large, randomized, placebo-controlled, double-blind trials of 12 to weeks' duration using dosages of 50 mg b.i.d. n 303 ; , 100 mg b.i.d. n 998 ; , and placebo n 973 ; . Efficacy was determined primarily by the change in maximal walking distance from baseline compared to change on placebo ; on one of several standardized exercise treadmill tests. Compared to patients treated with placebo, patients treated with Pletal 50 or 100 mg b.i.d. experienced statistically significant improvements in walking distances both for the distance before the onset of claudication pain and the distance before exerciselimiting symptoms supervened maximal walking distance ; . The effect of Pletal on walking distance was seen as early as the first on-therapy observation point of two or four weeks. The following figure depicts the percent mean improvement in maximal walking distance, at study end for each of the eight studies.

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